FAQS

FAQs

DNA Test is a simple saliva test, that provides DNA analysis and reports on your individual genetic response to different fitness and nutrition markers. Using the information from this report, you can make better‐informed choices about how to exercise and eat, on the most personal level possible–by taking your genetic profile into account.

One size does not fit all – we all are different and we live in the era of personalised services to suit your exercise and nutrition plans to include your genetic profile.unlock.fit’s DNA Test is just a simple saliva test but from this you’ll be provided with information to improve your health and fitness for a lifetime.Your genes do not change, but your lifestyle can.DNA Test looks at the interaction between genes and environment; by understanding your genetics you can better adjust your environment for your optimal health and fitness.Make the most of your time on the exercise by reducing guesswork/ trial and error with a new layer of truly personalised fitness information.Optimise your nutrition by knowing how your genetics affect the diet choices for your body.Our DNA Test is a new powerful tool in preventive wellbeing – we use genetics to help make the best informed choices when it comes to improving health through personalised fitness and diet.

Our DNA Test is the most comprehensive package that includes reports on:1. Nutrition,2. Fitness,3. Weight Loss,4. Detox profile,5. Food intolerance

Our comprehensive DNA Test report includes the following.Carbohydrate Sensitivite,Fat Sensitivity,Lactose intolerance,Coeliac predisposition,antioxidant requirement,Full vitamin and mineral profile,Omega-3 Need,Salt sensitivity,Caffeine sensitivity,Detoxification profile

The test includes 900,000 genetic variants, these are commonly known as SNP’s (Single Nucleotide Polymorphism). These are small changes in our DNA that make us individual. Different SNP’s affect everything from eye colour to weather we can taste the bitter flavour in foods like grapefruit. So naturally they affect our response to fitness and nutrition too.

Not at all. Genetic variation are simply the differences in the form of the gene you have so that you can make the right exercise, dietary and lifestyle choices to help you achieve your goals.

1. Sports genetics is the relationship between genetic science and exercise.2.Nutrigenetics is the relationship between genetic science, diet and nutrition.

It is important to note that your genes cannot tell us your goals or what your goal should be. Rather by understanding your genetic profile in the context of your goal, you will be able to use the information to better tailor your training and nutrition to reach your goal, whatever it may be. With advice from your trainer you will be able to tweak your existing training and diet to gain the best results and play to your genetic strengths.The key information when it comes to interpreting our test is that our genes interact with our environment to create who we are, or how we respond. Knowing our genes is the only half of the puzzle – we also need to manipulate our environment to get our desired health results.

The DNA test provides a report on the genetic variants you hold in relation to physical performance in general, regardless of your preferred sport or end goal.The DNA Test does provide some general recommendations to frame what is classed as a peer or endurance activity. Your preferred sports is a matter of personal preference, training history, desired goal and access to the appropriate infrastructure to pursue a sport. How best to perform for that chosen sport is then assisted by your trainer, who will be able to discuss how to implement the DNA Test results into your preferred sport / training method.

The DNA Test is not a medical tool and does not diagnose or offer therapeutic options for medical conditions. The DNA test is designed to give recommendations on optimising nutrition choices, which is all the more important when one’s health is not good, but it does not go beyond this. The same applies to exercise

This DNA Test is a one off test that provides you with life‐long information. Your genes never change. DNA testing is not the same as food intolerance testin which needs to be repeated regularly to monitor your antibodies in the blood. The recommendations contained in the reports will be valid for life. A simple tweak in your nutrition or exercise plan can optimise your health in the long run, therefore making the investment in this package more palatable.

This DNA Test is a one off test that provides you with life‐long information. Your genes never change. DNA testing is not the same as food intolerance testin which needs to be repeated regularly to monitor your antibodies in the blood. The recommendations contained in the reports will be valid for life. A simple tweak in your nutrition or exercise plan can optimise your health in the long run, therefore making the investment in this package more palatable.

No blood is needed Only Saliva samples is collected in a very convenient and easy No blood is needed. Only Saliva samples is collected in a very convenient and easy to use DNA Sample Kit. Full written step-by-step instructions are in the kit.

From the time the sample reaches the lab, your results will be delivered to you within 3-4 weeks. Once your results are ready, you will receive an automated email to schedule your one-on-one counselling session with our genetics expert. You will then get a highly personalized nutrition plan and access to our premium fitness sessions.

Your DNA sample is securely destroyed as per our lab quality manual and process.

If your sample fails to yield sufficient DNA, you will be notified of the same. We will provide you with another kit to complete the test. The lab will destroy your Saliva.It is important to read the instructions in detail to avoid any error, as any failed Saliva is usually due to an error in the saliva collection process.

The world of personal genetics is a fast growing industry, and there exist a number of companies operating in this space. However, not all tests are equal, with some providing guidelines on a very weak scientific base. As such, here’s our guide as to what to look for when selecting a DNA test: 1. Is there a full list of the genes that are tested available upon request? Some companies only look at just 6 genes – too few to base any justifiable assertions and recommendations upon. 2. Each gene included in a panel must have multiple peer-reviewed studies (tested on humans) that support the inclusion of this gene in the test. Statistically it’s likely that a gene that’s only supported by one study has a good chance of being a false positive and will negatively affect the accuracy of the test. Every single SNP p g y y y g reported in our test has reached a proven scientific consensus for its role. 3. Are the selected genes based on evidence from human studies, or animal studies? This may sound obvious, but surprisingly some companies make assumptions based on animal studies only! The SNPs that our DNA Test includes have all been shown for their activity on human subjects. 4. Does the company clearly display a code of practice on their website

At unlock.fit we concentrate on two fields – DNA testing for Diet i.e. Nutrigenetics and DNA testing for health, fitness and sport, sometimes referred to as Sports Genetics. We test very strictly only for genes associated with these two fields, and nothing more.Our aim is not to use genetics as any sort of “talent ID” or to use our genetic information to change someone’s goal, but rather to help tweak, adjust and improve the very best way to reach a health or fitness goal, whatever that may be. From managing our weight effectively, to training for the London marathon, we are trying to help to light the path as to the best way to reach an individual’s goal – using DNA as an extra parameter to further define the optimal training or nutrition (or of course both) to reach a given goal. Research has studied all the genetic variants we look at over many years, sometimes decades. Specifically we look for research studies that analyse both genetic variant AND lifestyle and the effect that the interaction has on a set endpoint, in our case, these end goals are all health and fitness based. This is called GEI (Gene x Environment Interaction) We take our scientific validity very seriously, in the process of selection we aim to establish the scientific validity of the gene x environment interaction and then the health or personal utility of the intervention via the following steps: 1. Search for relevant literature -‐ initial selection will be hundreds of abstracts 2. Selecting according to relevance. 3. Reasonable sample size study (actual size depends on study type – intervention, observational, etc – also key is the size of the subject group bearing the effect allele, this is often the minor allele) 4. Reputable journal with a strong impact factor. 5. Showing evidence of gene and environment effects -‐ Study in detail the promising candidates. The criteria for including the genetic variant (usually a single nucleotide polymorphism, SNP) are: 1. Common variants (generally >5% minor allele frequency) 2.The evidence is clear regarding the gene x environment effect 3. Documented positive effect of diet or lifestyle change 4. Repeated studies, at least 3 5.We have a strict code of practice that we adhere to (take a look here – one key thing is that we interpret the scientific data very carefully and do not claim any more than has been demonstrated, we don’t stretch it, extrapolate, or in any way go beyond what the data show (i.e. We stop, where the science stops!)

DNA testing can be applied to anyone regardless of the age.